Table 2 Summary of LMWH Trauma Studies Explicitly Reporting Incidence of HIT
| Study | Design | Type of LMWH | No. Patients | No. Cases of HIT |
|---|---|---|---|---|
| Geerts et al. 1996[10] | Randomized | |||
| UH 5,000 U SC BID vs. LMWH 30 mg SC BID | Enoxaparin | 171 | 2 | |
| Multi-system trauma & ISS ≥ 9 | ||||
| Haentjens et al. 1996[31] | Randomized | |||
| Fixed LMWH dose vs. Dose Adjusted LMWH | Nadroparin | 283 | 2 | |
| Orthopedic Trauma | ||||
| Schwarcz et al. 2001[32] | Retrospective | |||
| LMWH 30 mg SC BID | Enoxaparin | 234 | 1 | |
| Multi-system trauma | ||||
| Lubenow et al. 2007[30] | Prospective cohort | Certoparin | 460 | 0 |
| LMWH 3000u OD | ||||
| Multi-system trauma & orthopedic surgery | ||||
| Total | 5/1148 (0.4%) |