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Table 2 Summary of LMWH Trauma Studies Explicitly Reporting Incidence of HIT

From: Complications related to deep venous thrombosis prophylaxis in trauma: a systematic review of the literature

Study

Design

Type of LMWH

No. Patients

No. Cases of HIT

Geerts et al. 1996[10]

Randomized

   
 

UH 5,000 U SC BID vs. LMWH 30 mg SC BID

Enoxaparin

171

2

 

Multi-system trauma & ISS ≥ 9

   

Haentjens et al. 1996[31]

Randomized

   
 

Fixed LMWH dose vs. Dose Adjusted LMWH

Nadroparin

283

2

 

Orthopedic Trauma

   

Schwarcz et al. 2001[32]

Retrospective

   
 

LMWH 30 mg SC BID

Enoxaparin

234

1

 

Multi-system trauma

   

Lubenow et al. 2007[30]

Prospective cohort

Certoparin

460

0

 

LMWH 3000u OD

   
 

Multi-system trauma & orthopedic surgery

   

Total

   

5/1148 (0.4%)

  1. HIT, Heparin Induced Thrombocytopenia